Sunday, June 28, 2015

Week 3: To Each His (or Her) Own

7:30 am, morning rounds: port placements, PICC lines, drains, and biopsies with the occasional thrombolysis, stenting or tumor ablation thrown in for good measure. I have watched for three weeks the members of the interventional radiology (IR) division at New York Presbyterian Hospital discuss the same types of procedures for patient after patient.  After a while, one has to ask: why the repetition? Surely after years, or in the case of some of the attending physicians, decades of performing the same type of procedures they no longer need to discuss them.
            The problem with this seemingly logical conclusion is that no matter how many times a physician performs the same procedure each patient is different and each necessitates his or her own special considerations.  I witnessed a debate among the IR physicians this week about the best way to treat a particular patient with a thrombus.  One doctor was of the opinion that two days of anticoagulation (blood thinner medication) would be more effective than just a single day as was more standard.  All recognized that longer anticoagulation increased the risk of bleeding complications, but the physician in favor of longer anticoagulation believed that the risk was no longer particularly high for this patient despite a previous hematoma.  Upon hearing this conclusion, another physician responded “famous last words”.  He was clearly concerned that despite precautions taken against bleeding, the risk was too high.  In an otherwise perfectly healthy individual, the doctors would likely have easily agreed that two days of anticoagulation would be better, but the history of hematoma in this particular patient raised doubts.
            Besides history of previous disease, the age of a patient can drastically alter the way certain treatments are applied.  I watched a resident fellow put a peripherally inserted central catheter (PICC) into a 6 month old. This otherwise routine procedure became extremely complex due to the age of the patient. What is a small needle to an adult appears a deadly weapon next to such a young baby.  Wires and sheath’s had to be downsized, drugs diluted, and x-ray dose minimized.  Fellows and nurses from the neonatal department stood by to give advice.  Particularly complicated was the anesthesia.  Obviously, for one so young, general anesthesia rather than simple sedation was needed, yet even after the patient was completely asleep her continued movements necessitated the use of paralyzing drugs.  Although the main procedure lasted perhaps half an hour, the process of anesthetizing the patient and prepping her for the procedure took over an hour.
            Shadowing my mentor at the clinic, I saw that patient lifestyle also influences therapeutic decisions. For an athletic patient who made running, biking, and tennis a big part of his life, Dr. Sista considered a more aggressive treatment than he might otherwise in order to avoid the possibility of post-thrombotic symptoms that would interfere with this lifestyle.  When considering a particular treatment regime, he and others doctors carefully weigh a multitude of factors specific to that patient before deciding on the most optimal therapy.
            However, if the same patient sees two different physicians it is far from certain that they will receive the same treatment.  Much of medical decision-making is based on the physicians judgment, and just like their patients, every physician is different.  As a Ph.D. student, I have been trained to think objectively about everything.  Experiments must be carefully designed, decisions well supported by evidence and results reproducible.  At first the lack of uniformity and the unknown aspect of medicine jarred me.  Unfortunately, sufficient evidence is not always available for a fully scientific decision to be made.  Furthermore, clinicians do not have the option for waiting for more data; they have to make a decision when the patients need it. 

            The differences between clinicians and researchers became more obvious as I spoke to some of the visiting medical students.  As trainees in the medical field they seemed world’s ahead when it came to understanding medical procedures and diagnostic decisions, yet our roles completely reversed when it came to research.  As I worked on my summer research project I realized that the techniques that I took for granted and applied without thinking were foreign to them.  To each his own:  while the medical students delve into the complex world of clinical diagnosis, I will hopefully be researching new medical tools, techniques and therapies.  Perhaps together we can find cures for many human diseases. 

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